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Kinetex Core-Shell Technology Columns | Phenomenex

The Core-Shell Advantage

Kinetex Core-Shell Technology delivers dramatic improvements in efficiency over conventional fully porous media which can be leveraged to increase resolution, greatly improve productivity, reduce solvent consumption, and decrease costs. Whether you are running HPLC or UHPLC methods, the Kinetex core-shell family can deliver shockingly improved performance over the current column you are using. Phenomenex designs, manufactures, and sells its very own silica and organo-silica core-shell particles. The combination of a consistent, solid high density core along with proprietary column packing technologies ensures optimum bed structure and high column performance.

Citations (1)


(1) A high-throughput, simultaneous analysis of carotenoids, chlorophylls and tocopherol using sub two micron core shell technology columns.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
December 11, 2024
Chebrolu KK, Yousef GG, Park R, Tanimura Y, Brown AF

A high-throughput, robust and reliable method for simultaneous analysis of five carotenoids, four chlorophylls and one tocopherol was developed for rapid screening large sample populations to facilitate molecular biology and plant breeding. Separation was achieved for 10 known analytes and four unknown carotenoids in a significantly reduced run time of 10min. Identity of the 10 analytes was confirmed by their UV-Vis absorption spectras. Quantification of tocopherol, carotenoids and chlorophylls was performed at 290nm, 460nm and 650nm respectively. In this report, two sub two micron particle core-shell columns, Kinetex from Phenomenex (1.7μm particle size, 12% carbon load) and Cortecs from Waters (1.6μm particle size, 6.6% carbon load) were investigated and their separation efficiencies were evaluated. The peak resolutions were >1.5 for all analytes except for chlorophyll-a' with Cortecs column. The ruggedness of this method was evaluated in two identical but separate instruments that produced CV<2 in peak retentions for nine out of 10 analytes separated.

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Phenomenex is a global technology leader committed to developing novel analytical chemistry solutions that solve the separation and purification challenges of researchers in academic, pharmaceutical, biotech, environmental, clinical research, government, and industrial laboratories. From drug discovery and pharmaceutical...

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