Diagnostics: diagnosis based on information from sources such as findings from a physical examination, interview with the patient or family or both, medical history of the patient and family, and clinical findings as reported by laboratory tests and radiologic studies. Differential diagnosis involves the process of weighing the probability of one disease versus that of other diseases possibly accounting for a patient's illness. The differential diagnosis of rhinitis (a runny nose) includes allergic rhinitis (hayfever), the abuse of nasal decongestants and, of course, the common cold.
Training in your own institution or corporation can be challenging in trying to meet the goals of the program and the needs of the researchers. If you are challenged with training visiting in...
All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...
Rabbits are commonly used in biomedical research for many years due to its ease of use and phylogenetical similarities with humans. They are commonly used in cardiovascular research (atherosc...
Non-surgical transfer techniques for mouse embryos and sperm provide animal welfare benefits for assisted reproduction of mice. While surgical embryo transfer (ET) is an effective method for...
An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scien...
Nonhuman primates are commonly used in biomedical research due to its anatomical, behavioral, and genetic similarities with humans. Macaques, especially the Rhesus macaque (Macaca mulatta) ar...
GOAL:"A simple and reliable method for mouse intubation" is designed as an instructional tutorial with learning objectives that are twofold. First is becoming familiar with the procedure an...
In the laboratory setting, rats are commonly housed in clear caging in brightly lit rooms. As their natural history suggests a preference for low-light conditions, this practice is likely str...
Environmental enrichment can be defined as altering the living environment of captive animals in order to provide opportunities to express more of their natural behavioral repertoire. The cha...
Public concerns over animal experimentation are becoming felt on both sides of the Atlantic, and a dangerous chasm is appearing between those who conduct such experiments and those who are o...
The city of Valdivia is located in Chile, South America, 841 km south of its capital city Santiago. I moved to Valdivia early in 2004 to participate in the development of a new animal facilit...
The primary goal of all gnotobiotic facilities is to maintain a germ-free colony until such time as protocols require associations with other organisms. As such, a well-trained and knowledgea...
Contract Research Organizations present unique challenges in the field of environmental enrichment for laboratory animals. CRO's are service oriented and budget conscious, with large animal p...
The 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide NRC, 2011) has been in use since 2011. What changes has it brought? What are the impacts of those changes? The g...
Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
This presentation will discuss the properties of beddings on the market today and why the use of bedding alone does not promote thermoregulation. Topics included will be the importance of bed...
Abstract:
•General background, diagnostic and bio-marker implications of exosomes research
•Current solutions to purifying and identifying exosomes rapidly and accurately
•R...
2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
The development of CDx assays minimally requires a partnership between a pharmaceutical and a diagnostic company. It is not uncommon for the drug to be developed through an alliance of two ph...
As the scientific evidence base for pharmacogenetics continues to expand, the use of such information in clinical management and drug development will be in demand.
The FDA advises that the...
The discovery of proteinaceous disease biomarkers and their clinical validation is critically important for the enablement of molecular diagnostics and ultimately, precision medicine. In spit...
Curative therapy for metastatic disease in solid malignancies remains frustratingly elusive due to the long recognized problem of tumor cell heterogeneity and emergence of treatment resistant...
Cancer metastases develop when tumor cells known as circulating tumor cells (CTCs) are shed from a tumor, circulate through the blood stream and colonize a distant tissue. The number of CTCs...
Whenever there is cell death, apoptotic cell free DNA fragments appear in the circulation of the host. These fragments, typically 145-160 base pairs in size, represent a minute fraction of to...
Training in your own institution or corporation can be challenging in trying to meet the goals of the program and the needs of the researchers. If you are challenged with training visiting in...
All personnel involved in an animal care and use program are expected to have an appropriate level of education, training and/or qualifications to perform their duties as defined through laws...
Rabbits are commonly used in biomedical research for many years due to its ease of use and phylogenetical similarities with humans. They are commonly used in cardiovascular research (atherosc...
Non-surgical transfer techniques for mouse embryos and sperm provide animal welfare benefits for assisted reproduction of mice. While surgical embryo transfer (ET) is an effective method for...
An anesthesia system designed to accommodate the physiological characteristics of small animals, including rats and mice, has the potential to provide great practical value to the life scien...
Nonhuman primates are commonly used in biomedical research due to its anatomical, behavioral, and genetic similarities with humans. Macaques, especially the Rhesus macaque (Macaca mulatta) ar...
GOAL:"A simple and reliable method for mouse intubation" is designed as an instructional tutorial with learning objectives that are twofold. First is becoming familiar with the procedure an...
In the laboratory setting, rats are commonly housed in clear caging in brightly lit rooms. As their natural history suggests a preference for low-light conditions, this practice is likely str...
Environmental enrichment can be defined as altering the living environment of captive animals in order to provide opportunities to express more of their natural behavioral repertoire. The cha...
Public concerns over animal experimentation are becoming felt on both sides of the Atlantic, and a dangerous chasm is appearing between those who conduct such experiments and those who are o...
The city of Valdivia is located in Chile, South America, 841 km south of its capital city Santiago. I moved to Valdivia early in 2004 to participate in the development of a new animal facilit...
The primary goal of all gnotobiotic facilities is to maintain a germ-free colony until such time as protocols require associations with other organisms. As such, a well-trained and knowledgea...
Contract Research Organizations present unique challenges in the field of environmental enrichment for laboratory animals. CRO's are service oriented and budget conscious, with large animal p...
The 8th Edition of the Guide for the Care and Use of Laboratory Animals (Guide NRC, 2011) has been in use since 2011. What changes has it brought? What are the impacts of those changes? The g...
Simplifying Rodent Surgery... Tips for improving technique without incurring unreasonable costs Good science is greatly dependent on minimization of study variables. Surgery has the potential...
This presentation will discuss the properties of beddings on the market today and why the use of bedding alone does not promote thermoregulation. Topics included will be the importance of bed...
Abstract:
•General background, diagnostic and bio-marker implications of exosomes research
•Current solutions to purifying and identifying exosomes rapidly and accurately
•R...
2013 has proven to be a year of paradigmatic shifts in molecular diagnostics reimbursement policy. In this session, we will review and analyze these key policy and payment developments and di...
The development of CDx assays minimally requires a partnership between a pharmaceutical and a diagnostic company. It is not uncommon for the drug to be developed through an alliance of two ph...
As the scientific evidence base for pharmacogenetics continues to expand, the use of such information in clinical management and drug development will be in demand.
The FDA advises that the...
The discovery of proteinaceous disease biomarkers and their clinical validation is critically important for the enablement of molecular diagnostics and ultimately, precision medicine. In spit...
Curative therapy for metastatic disease in solid malignancies remains frustratingly elusive due to the long recognized problem of tumor cell heterogeneity and emergence of treatment resistant...
Cancer metastases develop when tumor cells known as circulating tumor cells (CTCs) are shed from a tumor, circulate through the blood stream and colonize a distant tissue. The number of CTCs...
Whenever there is cell death, apoptotic cell free DNA fragments appear in the circulation of the host. These fragments, typically 145-160 base pairs in size, represent a minute fraction of to...
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