Gene Editing: a type of genetic engineering in which DNA is inserted, deleted or replaced in the genome of a living organism using engineered nucleases, or "molecular scissors". These nucleases create site-specific double-strand breaks (DSBs) at desired locations in the genome. The induced double-strand breaks are repaired through nonhomologous end-joining (NHEJ) or homologous recombination (HR), resulting in targeted mutations.
CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering. The delivery of Cas9 plasmid DNA or mR...
The development of the CRISPR/Cas9 gene-editing platform enables the rapid generation of new genetically modified stem cell models of human diseases, as well as providing new potential therap...
The emergence of technology for development of induced pluripotent stem cells (iPSCs) from somatic cells, such as skin and blood cells, has resulted in the ability of researchers to have limi...
DATE: May 31, 2017TIME: 9:00AM PDT, 12:00PM ETAlthough more remains to be learnt, great advances have recently been made in the understanding of the molecular & genetic bases of dis...
CRISPR-Cas9 has increased the accessibility of genome engineering due to its ease of use and ability to cause double strand breaks (DSBs) at almost any locus of interest. DSBs are repaired in...
The use of pluripotent stem cell-derived cell types for disease modeling, drug screening and regenerative medicine is an exciting area of activity in health research. Prior to the availabilit...
The CRISPR-Cas9 system is being widely used for genome engineering in many different biological applications. It was originally adapted from the bacterial Type II CRISPR system and uses a Cas...
DATE: February 9, 2017TIME: 3:00pm PT, 6:00pm ETThe presentation will very briefly cover the regulatory system for lab animals in China, as well as the regulations and guidelines a...
DATE: February 9, 2017TIME: 3:00pm PT, 6:00pm ETA colony of woodchucks were to be used on studies which involved repeated IV dosing and/or multiple blood collection time points. Some of...
DATE: February 9, 2017TIME: 1:30pm PT, 4:30pm ETThe animal research field has gotten more sophisticated with the use of genetically engineered animals, biohazardous agents, and advanced...
DATE: February 9, 2017TIME: 12:00pm PT, 3:00pm ETThe presentation will develop the FELASA (Federation of the European Laboratory Animal Science Association) views on education and train...
DATE: February 9, 2017TIME: 10:30am PT, 1:30pm ETDuring the last 50 years the claims for continuous development and training of laboratory animal staff has been progressively devel...
DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETTraditional models of liver fibrosis in rodents involve many weeks of induction, with frequent injections of a pro-fibrotic agent. The m...
DATE: February 9, 2017TIME: 6:00am PT, 9:00am ETThere is no professional area in which CPD is more necessary than in the field of laboratory animals. The continuous advancement of scien...
DATE: February 9, 2017TIME: 6:00am PT, 9:00am ETThe University of Michigan’s Unit for Laboratory Animal Medicine (ULAM) has a diverse Training Core that teaches a wide varie...
DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETMeloxicam is an analgesic NSAID commonly used in mice. Anecdotal evidence supports the use of alternative delivery methods for analgesics...
DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETThe Eastern woodchuck (Marmota monax) is a large, burrowing rodent with native territories throughout parts of the US and Canada. Woodchu...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETThe powerful and expanding use of genetically modified mice introduces important aspects of genetics in managing these strains for breedi...
DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETLarge animal models have recently become a staple in biomedical research. The pig’s similarities to humans in terms of genet...
DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETIn-vivo surgical models are becoming more prevalent and more critical to the drug development process. As the vast majority of ind...
DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe utility of animal models in drug development is limited, in part, by the measures available to researchers for monitoring animals. I...
DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
CRISPR-Cas9 systems provide a platform for high efficiency genome editing that are enabling innovative applications of mammalian cell engineering. The delivery of Cas9 plasmid DNA or mR...
The development of the CRISPR/Cas9 gene-editing platform enables the rapid generation of new genetically modified stem cell models of human diseases, as well as providing new potential therap...
The emergence of technology for development of induced pluripotent stem cells (iPSCs) from somatic cells, such as skin and blood cells, has resulted in the ability of researchers to have limi...
DATE: May 31, 2017TIME: 9:00AM PDT, 12:00PM ETAlthough more remains to be learnt, great advances have recently been made in the understanding of the molecular & genetic bases of dis...
CRISPR-Cas9 has increased the accessibility of genome engineering due to its ease of use and ability to cause double strand breaks (DSBs) at almost any locus of interest. DSBs are repaired in...
The use of pluripotent stem cell-derived cell types for disease modeling, drug screening and regenerative medicine is an exciting area of activity in health research. Prior to the availabilit...
The CRISPR-Cas9 system is being widely used for genome engineering in many different biological applications. It was originally adapted from the bacterial Type II CRISPR system and uses a Cas...
DATE: February 9, 2017TIME: 3:00pm PT, 6:00pm ETThe presentation will very briefly cover the regulatory system for lab animals in China, as well as the regulations and guidelines a...
DATE: February 9, 2017TIME: 3:00pm PT, 6:00pm ETA colony of woodchucks were to be used on studies which involved repeated IV dosing and/or multiple blood collection time points. Some of...
DATE: February 9, 2017TIME: 1:30pm PT, 4:30pm ETThe animal research field has gotten more sophisticated with the use of genetically engineered animals, biohazardous agents, and advanced...
DATE: February 9, 2017TIME: 12:00pm PT, 3:00pm ETThe presentation will develop the FELASA (Federation of the European Laboratory Animal Science Association) views on education and train...
DATE: February 9, 2017TIME: 10:30am PT, 1:30pm ETDuring the last 50 years the claims for continuous development and training of laboratory animal staff has been progressively devel...
DATE: February 9, 2017TIME: 9:00am PT, 12:00pm ETTraditional models of liver fibrosis in rodents involve many weeks of induction, with frequent injections of a pro-fibrotic agent. The m...
DATE: February 9, 2017TIME: 6:00am PT, 9:00am ETThere is no professional area in which CPD is more necessary than in the field of laboratory animals. The continuous advancement of scien...
DATE: February 9, 2017TIME: 6:00am PT, 9:00am ETThe University of Michigan’s Unit for Laboratory Animal Medicine (ULAM) has a diverse Training Core that teaches a wide varie...
DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETMeloxicam is an analgesic NSAID commonly used in mice. Anecdotal evidence supports the use of alternative delivery methods for analgesics...
DATE: February 8, 2017TIME: 3:00pm PT, 6:00pm ETThe Eastern woodchuck (Marmota monax) is a large, burrowing rodent with native territories throughout parts of the US and Canada. Woodchu...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETIn rabbits, buprenorphine instant release (IR) is commonly used to alleviate pain, especially in surgical models. However, maintenan...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETPerlara PBC, is a public benefit company committed to discovering small molecule therapeutics for rare genetic diseases. Our approach con...
DATE: February 8, 2017TIME: 1:30pm PT, 4:30pm ETThe powerful and expanding use of genetically modified mice introduces important aspects of genetics in managing these strains for breedi...
DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETLarge animal models have recently become a staple in biomedical research. The pig’s similarities to humans in terms of genet...
DATE: February 8, 2017TIME: 12:00pm PT, 3:00pm ETIn-vivo surgical models are becoming more prevalent and more critical to the drug development process. As the vast majority of ind...
DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe utility of animal models in drug development is limited, in part, by the measures available to researchers for monitoring animals. I...
DATE: February 8, 2017TIME: 10:30am PT, 1:30pm ETThe cat remains an important comparative species for studying the long-term safety and efficacy of emergent medical modalities, such as...
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